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Studies by CMC kidney specialists published on the Elsevier Health and Science Journal

The Correlation of Renal Allograft Weight to Metabolic Index Ratios and Glomerular Filtration Rate Among Living-Unrelated Kidney Transplant Patients: A Cross-Sectional Study”

Published in Elsevier Health and Science Journal (www.elsevier.com), 12 September 2008

By A.J. Amante and S.C. Piñon-Barretto

Abstract - Objective

This study sought to determine whether there was a relationship between the ratios of renal allograft weight (RAW) and metabolic indices: specifically, recipient body weight (RBW), recipient body mass index (RBMI), and recipient body surface area (RBSA), and posttransplant renal function as measured by glomerular filtration rate (GFR).

It also sought to determine which of the 3 ratios, and the minimum ratio, that was predictive of a good GFR as well as to ascertain which computational formula (Cockroft-Gault [C&G] vs abbreviated Modification of Diet in Renal Disease [aMDRD]) better predicts renal function.

Link to the complete article published by Elsevier can be found here.

Kidney transplantation

Management of Highly Sensitized Patients: Capitol Medical Center Experience

Published in Elsevier Health and Sciences Journal (www.elsevier.com) 12 September 2008

By A.J. Amante and R. Ejercito

Abstract

Highly sensitized patients with elevated anti-HLA antibodies have difficulty to get a living donor due to cross-match positivity and longer waiting times for cadaveric donor transplantation. In this regard, several studies have been made to abrogate cross-match positivity for a possible successful kidney transplantation.

In this article, we report our experience, using a desensitization protocol with Rituximab monoclonal antibody complemented with intravenous immunoglubulin and/or plasmapheresis, to prepare highly sensitized patients for successful kidney transplantation.

The full study can be found here.